5 Best CBD Oil for Anxiety

According to the Anxiety and Depression Association of America (ADAA), anxiety disorders are one of the most common mental illnesses and issues in the USA, affecting around 40 million adults in the country, with women in the majority. More specifically, around 6.8 million are diagnosed with Generalized Anxiety Disorder (GAD), which some are also diagnosed with major depression. Meanwhile, around 6 million are suffering from panic disorder (PD), 15 million are reported to have Social Anxiety Disorder (SAD), and around 19 million are affected with Specific Phobias. We also have obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) as the other two mental health issues are closely related to anxiety disorders.

Only 43.2% of people suffering from Generalized Anxiety Disorder are getting appropriate treatment. Some even look for alternatives such as CBD to reduce the cost. So, what is the best CBD oil for anxiety and depression? What are its proper dosage and side effects? Is CBD good for anxiety and depression? Read on to find out.

What Is CBD and How Does It Work?

CBD is a short term for “cannabidiol”. This is one of the healthy cannabinoids or a compound found in cannabis plants. When you hear the term cannabis, some people immediately associate it with marijuana. However, there is another plant that belongs to the cannabis family, the hemp plant.

CBD is different from THC (tetrahydrocannabinol). Unlike THC, CBD will not make you feel high, or we can say it will not cause any psychoactive effect. While both CBD and THC can be found in marijuana and hemp, CBD products in the market use hemp as the source of CBD oils.

While the study about the long-term efficacy and benefits of CBD is still ongoing, there is already research available, suggesting that the use of CBD can help manage certain health conditions such as chronic pain and inflammation, Alzheimer’s disease, Parkinson’s disease, Acne, Type 1 diabetes, and Cancer-related symptoms. It also alleviates the symptoms of certain mental health conditions like anxiety and depression, Insomnia, and PTSD, and psychotic symptoms.

Basically, CBD makes a certain interaction to our nervous system, where the brain is at its center and receptors as the helpers. More specifically, it works with our endocannabinoid system. It is said to have anti-inflammatory properties, pain relief, and anti-anxiety effects.

Editor’s Choice


  • US grown hemp
  • Lab-tested products
  • Full-spectrum CBD

Best CBD Oil for Anxiety and Depression: Top 5 Brands in 2021

  1. FAB CBD – Editor’s pick
  2. NuLeaf Naturals – Most potent full-spectrum
  3. Green Roads – Large product variety
  4. CBDistillery – Wide range
  5. Cheef Botanicals – Strongest mission




  • Lab-tested
  • Full-spectrum CBD


  • Easily sold out

Click here to get the best deal on FAB CBD

FAB is one of the leading CBD brands offering high-quality CBD products such as CBD gummies for anxiety, CBD oil, and CBD topicals. They started their business in October 2017. Although they are somewhat new in the industry, they have a strong foundation to be able to deliver high-quality CBD oils for anxiety and other CBD products.

Being well-known for their top-rated CBD oil, they make their products undergo third-party lab tests. They are also transparent, making the lab results available to the public. If you want to see the lab test results of the product you bought, you can simply head over to their website, and you will see all the results once updated.

Their hemp source is from farms in Colorado, USA. Their CBD oils for anxiety come from a full-spectrum hemp extract to let you gain its maximum benefit. Rest assured that while it is full-spectrum, only less than 0.3% THC.

Furthermore, they use CO2 extraction methods. Plus, you will have a variety of options in terms of potency and flavors. For strength, you can choose among 300mg, 600mg, 1200mg, and 2400mg of CBD per bottle. As for the flavor options, you have natural or unflavored, vanilla, berry, citrus, and mint. However, all options are only available in a 30ml-sized bottle.

Regardless of what CBD oil for anxiety you choose, FAB CBD uses MCT oil as its carrier oil. That further improves their products, as it enhances the absorption of all the hemp oil compounds.

Lastly, they are happy to offer free shipping in orders within the United States when your price order reaches $89. A 30-day money-back guarantee is also available for all customers.

2. NuLeaf Naturals




  • Limited variety of products

Click here to get the best deal on Nuleaf Naturals

One of the pioneering CBD brands in the industry is NuLeaf Naturals. If you want to shop for CBD oils for anxiety and depression, this can be a great consideration, as the company mainly focuses on CBD oil tinctures both for humans and for animals.

Men behind NuLeaf Naturals are health-conscious herbal medicine enthusiasts. The team started their company in 2014, the same year when industrial hemp cultivation became legal in the US. They formulate one of the best CBD oils through the CO2 extraction method. Aside from that, all their CBD oils are made from a full-spectrum hemp extract.

All the manufacturing practices are verified by third-party labs, which results can be accessed on their website. From there, you can confirm that their CBD oils for anxiety are 100% pure, clean, and free from harmful substances such as pesticides, insecticides, heavy metals, and other chemicals. Moreover, their third-party lab-testing facility is ISO-17025 certified for quality and accuracy.

As for the source of hemp oil, their CBD oil is made from organic hemp that was grown from the state of Colorado. As they use CO2 extraction for their hemp oil, they apply both its advanced subcritical and supercritical versions. Plus, the company has also been cGMP certified. This means that they are complying with the FDA’s current Good Manufacturing Practices.

Currently, NuLeaf Naturals has two types of CBD for anxiety. One is their full-spectrum hemp oil, and the other is their full-spectrum CBD capsules. Their CBD oil is available in varying potencies. Feel free to choose among 300mg, 900mg, 1800mg, 3000mg, and 6000mg. It is also available in different bottle sizes, 5ml, 15ml, 30ml, 50ml, and 100ml. Each contains 60mg of CBD per ml.

3. Green Roads



  • Vegan-friendly
  • Full-spectrum


  • Limited product range

Click here to get the best deal on Green Roads CBD

Green Roads is also one of the pioneering CBD brands in the US. It started to emerge in 2013, right before CBD oil derived from hemp plants was legally accepted. The men behind the company are Laura Fuentes and Arby Barroso.

Barroso was suffering from a difficult-to-handle health issue, while Fuentes was a full-time pharmacist. Fuentes wanted to help Barroso overcome his health problem. Thus, they teamed up.

Later, the two made a collaboration with other two people, Danny Perdeck and Jimmy Tundidor. Their great team made them successfully sell their products, as they continue their mission: to help people obtain their healthiest version of themselves.

To offer high-quality CBD oils, Green Roads employs third-party lab tests for all its CBD products. All the product’s lab test results are available on their website. From there, you can double-check your CBD oil, whether it contains artificial ingredients and/or harmful substances or not.

They also get their hemp in farms of Colorado and use CO2 extraction for their hemp extract. Another thing that makes them unique is their CBD oil is vegan-friendly. However, their CBD oils are sometimes out of stock, because of the high demand in the market.

Green Roads CBD is available in different potency levels. Their mildest CBD oil contains 300MG of CBD per bottle. The moderate potency contains 750MG of CBD, and the strongest contains 1500MG of CBD per package. All of these are in the form of a full spectrum.

Lastly, Green Roads CBD offers free shipping. All you must do is make an order reaching $100.00.

4. CBDistillery



  • Current good manufacturing practices
  • Broad-spectrum CBD, full-spectrum CBD, and more


  • No flavor variety

Click here to get the best deal on CBDistillery

Another one of the CBD brands offering the best CBD oil for anxiety is CBDistillery. The company was established in 2016, and it is best known as an American CBD brand focusing on the easy access of their customers to their high-quality, industrial hemp-derived CBD products.

When you go to their website, you will not only see their products and certain information about their company. They have also put up informational articles such as articles discussing CBD health benefits, scientific researches, and additional offers. Also, CBDistillery is known for being transparent with its products. As such, they allow their CBD oils for third-party lab testing, which is also ISO 17025-accredited.

To access the certificate of analysis (COA) of the third-party lab-tested CBD oil you got from the company, simply scan the QR code found on the label of your CBD oil. You can also see the COA overview of the specific product even if you will just browse their site. Furthermore, CBDistillery has been certified by the U.S. Hemp Authority (USHA), which means that the company is following the CBD standards such as in terms of ingredients and labeling.

In 2019, the said company obtained generally recognized as safe or (GRAS) status after their products had been reviewed by several toxicologists. CBDistillery is a member of the US Hemp Roundtable and the National Hemp Association. Furthermore, the Colorado Department of Public Health and Environment is there to help them sustain and improve their manufacturing facility. This means that they employ current good manufacturing practices (CGMP), with ISO-9001 certification.

As for the variety of selections, their CBD oil for anxiety is available in different types and potency levels. You can choose whether you want a full-spectrum, CBD, broad-spectrum, CBD and pure CBD, which we also call THC-free CBD or CBD isolate. For the potency level, you can choose among 500mg, 1000mg, and 2500mg. Unfortunately, all CBDistillery CBD oils are unflavored.

5. Cheef Botanicals



  • Organically grown hemp from the US
  • Full-spectrum CBD
  • Vegan-friendly


  • Unflavored products

Click here to get the best deal of Cheef Botanicals

Cheef Botanicals is one of the CBD brands that offer CBD oil for anxiety and other products. Some of those are CBD flowers, edibles, concentrate, topicals, vape cartridges, and CBD for pets. Being the one who has a strong mission, the company aims to educate the world about the health benefits that CBD can offer.

CBD oils from Cheef Botanicals are safe to use. Its founders are a team of professionals, whose experiences were focused on the food industry. They also have their product be third-party lab-tested to ensure that all CBD products are clean. More specifically, their CBD oils are potent, pure, dairy-free, non-GMO, and gluten-free.

Furthermore, Cheef Botanicals uses CO2 extraction methods in extracting their hemp. Their source of hemp farms in Colorado and Oregon, two of the top-rated and highly reputable farms in the US. Plus, all their products are vegan-friendly.

For the potency and the type of CBD, Cheef Botanicals’ CBD oil for anxiety is in the form of full-spectrum CBD oil. Its lowest potency is 300mg, and the highest is 3000mg.

Why is CBD oil Good for Anxiety?

It is good to keep in mind that studies about CBD and its possibility of treating anxiety are still ongoing. However, there are already different studies that can support this claim. For instance, the report of the National Institute on Drug Abuse (NIDA) and the National Institutes of Health (NIH) showed several CBD potential therapeutic effects such as neuroprotective, Anti-Inflammatory, antiPsychotic, and anti-Anxiety Effects. By that means, CBD can affect sleep, mood, digestion, and behavior.

Meanwhile, it has been found out that regulating the level of serotonin helps the treatment of anxiety. The same applies to treating major depression. As for the CBD, there is a study stating that CBD affects the brain similar to how antidepressants do.

Here is another study by José Alexandre S Crippa regarding the effects of CBD on people suffering from anxiety. The research also showed a substantial positive effect in reducing anxiety symptoms. Moreover, Esther M. Blessing and the team also published another study, which showed the potential benefits of CBD in different types of anxiety disorders and related mental illnesses. This includes generalized anxiety disorder (GAD), panic disorder, social anxiety disorder, and other two related mental conditions called obsessive-compulsive disorder (OCD) and post-traumatic stress disorder (PTSD).

Also, there are two studies conducted in 2019. One is focusing on the effects of CBD in PTSD, a mental condition that sometimes shares symptoms with anxiety. According to the research, 91% of the subjects experienced reduced symptoms after taking CBD. The other study was focusing on anxiety and sleep disturbances. Within the first month of the experiment, around 70% had an improvement.

Best CBD Oil Dosage for Anxiety

It is true that CBD oil can deliver various health benefits such as treating anxiety and depression. Yet, it does not mean that you can take just any amount. There is a proper dosage for everything.

The best CBD oil dosage to treat anxiety depends on different factors. These include your body weight, your individual, unique body chemistry, and the CBD concentration per serving. If you have another health condition to treat, that should also be put into consideration.

Consult Your Doctor

Before trying out CBD, it is always recommended to consult your doctor or any of your health providers. They can recommend a good CBD dosage for you. Of course, your doctor must know about your medical history, especially your current health status and ongoing medication and/or treatment including other medicines you take.

Start With a Low Dose

If your doctor does not prescribe you CBD but still wants to try, the next best thing to do is starting at the lowest dosage as you can. You can gradually increase the dose if you think you are not getting the results you want to achieve. However, be aware of the possible side effects. It may be an indication of an overdose.

Follow the CBD Brand’s instruction

Some CBD brands release their product with information on how to take a specific product. You may see it either on the product label or on their website. You can follow them if your doctor did not prescribe any CBD limitation. Lower the dose if you start experiencing negative effects.

What Happens If You Use Too Much CBD Oil?

There is no study stating that too much intake of CBD can cause death in humans. However, taking too much CBD will cause unpleasant effects in your body, which may affect your entire day. Some of these unpleasant effects are drowsiness, lethargy, nausea, upset stomach, and diarrhea.

Common Side Effects of CBD

Few common side effects of CBD have been mentioned above (drowsiness, lethargy, nausea, upset stomach, and diarrhea). However, these side effects are more common when you have taken too much of them. In some cases, especially if you are just starting out, you may also experience changes in weight and your appetite. Feeling tired or fatigue is also common, but lowering the dose a little bit usually solves the problem.


As highlighted by Erik Pham and the medical team in some articles in HealthCanal newspaper, CBD may be a potential treatment for anxiety, as well as depression. Using CBD oil products is generally safe to use. You may experience negative effects, but many people who use CBD for anxiety do not experience any. Nevertheless, there is proper dosage for it.

Indeed, it is good to consult your doctor before you use CBD oil, whether it will be a pure CBD, CBD isolate, THC-free, broad-spectrum CBD, or full-spectrum CBD oil. Also, be reminded that the FDA does not regulate CBD use, even though it is legal to use CBD, which is derived from organically grown hemp within reputable US farms. CBD extracts from marijuana and not from hemp is still not legal, as it may contain high THC.

So, if you want to get the best CBD that can help with anxiety, find a CBD brand that uses organic hemp as its source of CBD extract. The Cbd product should also be third-party tested in labs, and results should be available on the brand’s website.

Frequently Asked Questions

Q: Is CBD oil safe for depression and anxiety?

Generally, CBD oil is safe for depression and anxiety. However, it may react to other medications or treatments that you have (if there is). Consult your doctor first if you are taking antidepressants, antianxiety, and/or psychotropic medications to avoid conflict.

Q: Can doctors prescribe CBD for anxiety?

Yes, doctors can prescribe CBD for anxiety, and even for depression.

Q: Can 25 mg of CBD help with anxiety?

Yes, 25mg of CBD oil may help in the treatment for anxiety disorders. It can reduce symptoms of anxiety including panic attacks. You can slowly increase your use of CBD for anxiety if necessary.

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